Assemblies for diagnostics, imaging and therapy

1-Introduction 1.1-Reminders on bioactive molecules (drugs, nucleic acids, proteins) in interaction with polymer systems 1.2-Medical diagnostics: definition, challenges, ELISA method 1.3-Medical imaging: presentation of the major imaging techniques 1.4-Therapy: role of drug delivery systems, pharmacokinetics, pharmacodynamics, targeting methods 1.5-Interaction modes between polymer systems and-bioactive molecules 2- Colloids 2.1-Colloids obtained from preformed polymers

• Polyesters: their synthesis, their formulation into colloidal systems, drug encapsulation and release
• Polyelectrolyte complexes as protein carriers 2.2- Application of colloids to in vitro medical diagnostics 2.3- Lipid-based colloids Elaboration, characterization, surface modification, drug encapsulation, diagnostic, therapeutic and dermatologic applications 3- Water-soluble polymers and hydrogels 3.1-Elaboration of water-soluble polymer / biomolecule conjugates (polyelectrolytes, neutral polymers, amphiphilic polymers) for in vitro diagnostics, medical imaging and drug delivery. 3.2-Hydrogels: elaboration, applications to drug delivery and as artificial organs.